Amiloidosis

Is a disease in which amyloid (a protein not normally found in the body) are found and accumulated in the body. Several forms of amyloidosis: 

1. Primary amyloidosis. The cause is unknown. The disease is associated with abnormal plasma cells. 

2. Secondary amyloidosis. Amyloidosis occurs secondary to other diseases such as tuberculosis, rheumatoid arthritis, familial Mediterranean fever or granulomatous ileitis. 

3. Hereditary amyloidosis. Regarding specific nerves and organs. Many occurred in people from Portugal, Sweden, Japan and many other countries.

Cause
The cause of amyloid in the body stack is still unknown. But amyloidosis can occur in response to the various diseases that cause inflammation or infection. 

Symptom
Accumulation of large amounts of amyloid can menggganggu normal function of various organs. Symptoms of amyloidosis depend on the location where these proteins accumulate. In primary amyloidosis, amyloid accumulated in the heart, lungs, skin, tongue, thyroid gland, intestines, liver, kidneys and blood vessels. 

This buildup can cause:
- Heart failure
- Irregular heartbeat
- Difficulty breathing
- Thickening of the tongue
- Hipoaktivitas thyroid gland
- Reduced ability to absorb food
- Liver failure
- Kidney failure
- Easy bruising or other abnormal bleeding because of its effect on blood clotting process. 

Abnormalities of nerve function causes weakness and abnormal sensations. It could also happen Carpal tunnel syndrome. When the heart, death can occur due to severe heart failure or irregular heart beats. 

In secondary amyloidosis, amyloid tends to accumulate in the liver, spleen, kidneys, adrenal glands and lymph nodes. Liver and spleen enlarged and palpable demarcated and chewy. Other organs and blood vessels can be affected, although the heart is rarely involved. 

Handling
Amyloidosis does not always require treatment. When the cause is other diseases, treatment of the disease will usually slow down or even eliminate amyloidosis. Accumulation of amyloid (amyloid tumor) in a particular body part can sometimes be removed surgically. 

Patients whose kidneys can be damaged due to undergo a kidney transplant amyloidosis. Patients who have heart problems, could undergo heart transplantation. But the organ is transplanted, will also be exposed to amyloid buildup.